The Litegua bus from Río Dulce to Guatemala City takes about six and a half hours and costs Q80 ($10.65). The Litegua bus is air conditioned, has curtained windows, reclining seats, assigned seating and a basic toilet. The buses have several televisions installed and often play movies during travel.
The Litegua bus from Río Dulce to Guatemala City isn't a tourist bus. It's often fairly full and is patronized mostly by nationals. Earlier buses are less crowded. The bus makes one meal stop en route from Río Dulce to Guatemala City, unless you take the earliest bus (3:00 AM) which goes direct. Large luggage is stored beneath the bus, smaller luggage can be carried on.
There are other buses from Río Dulce to Guatemala City, but the Litegua is the most comfortable and is a great value at Q80 ($10.65) per passenger. Litegua buses are secured by security personnel. Customers are briefly searched before boarding.
If you book your passage on the bus from Río Dulce to Guatemala City the night before, you'll secure a seat closer to the front of the bus which means easier entry and exit when the bus stops. You can call the Río Dulce Litegua agency at (502) 7930-5251. Most agents speak only Spanish.